Binazzi A, Scarselli A, Corfiati M, Di Marzio D, Branchi C, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallenberg G, Merler E, De Zotti R, Romanelli A, Chellini E, Pascucci C, D'Alò D, Forastiere F, Trafficante L, Menegozzo S, Musti M, Cauzillo G, Leotta A, Tumino R, Melis M, Marinaccio A; Gruppo di lavoro ReNaM.

Epidemiol Prev. 2013;37(1):35-42.



To show how malignant mesothelioma (MM) surveillance not only identifies settings of exposure representing past industrial history, but it may also detect conditions of current exposure relevant for the prevention, if the wide spectrum of asbestos uses is considered.

Active search of MM cases and exposure assessment at individual level through a questionnaire; identification of exposure circumstances relevant for prevention.

Italy, all the Regions where a Regional Operating Centre (COR) is established to identify all MM cases diagnosed in the population and analyze their occupational, residential, household and environmental histories. Period of diagnosis: 1993-2008.

Descriptive analysis of MM cases and of asbestos exposures.

ReNaM includes 15,845 cases of MM diagnosed between 1993 and 2008.The male/female ratio is 2.5. Mean age at diagnosis is 69 years. Pleural MMs represent 93% of all cases. Exposures have been investigated in 12,065 cases (76%). The median latency time is 46 years. In addition to clusters of MM cases in activities well known to entail asbestos use, different current exposure circumstances requiring intervention have been evidenced.

On the basis of this experience, epidemiological surveillance of all occupational cancers should be implemented to foster synergies with the compensation system and the Local Health Authorities' occupational safety and health services, as required by the Italian Legislative Decree N. 81/2008.