{"id":3187,"date":"2022-11-03T11:04:22","date_gmt":"2022-11-03T11:04:22","guid":{"rendered":"https:\/\/www.registrotumoriveneto.it\/2022\/11\/03\/impact-of-microscopic-confirmation-on-therapeutic-management-of-pancreatic-cancer-patients-lessons-from-an-italian-regional-tumor-registry\/"},"modified":"2022-11-03T11:04:22","modified_gmt":"2022-11-03T11:04:22","slug":"impact-of-microscopic-confirmation-on-therapeutic-management-of-pancreatic-cancer-patients-lessons-from-an-italian-regional-tumor-registry","status":"publish","type":"post","link":"https:\/\/www.registrotumoriveneto.it\/en\/english\/publications\/research-publications\/2022\/impact-of-microscopic-confirmation-on-therapeutic-management-of-pancreatic-cancer-patients-lessons-from-an-italian-regional-tumor-registry\/","title":{"rendered":"Impact of Microscopic Confirmation on Therapeutic Management of Pancreatic Cancer Patients: Lessons from an Italian Regional Tumor Registry"},"content":{"rendered":"<p><em>Fantin A, Gruppo M, De Simoni O, Lonardi S, Cristofori C, Morbin T, Peserico G, Grillo S, Masier A, Franco M, Pilati P, Guzzinati S, Zorzi M, Rugge M.<\/em><\/p>\n<p><em>Cancers (Basel). 2022 Oct 31;14(21):5372. doi: 10.3390\/cancers14215372.<\/em><\/p>\n<p><!--more--><\/p>\n<p><strong>Abstract<\/strong><\/p>\n<p>Background: Incidence of pancreatic cancer (PC) is increasing worldwide and is set to become the second leading cause of cancer-related death in 2040 with a poor 5-year overall survival (OS). The aim of this study was to analyze the impact of microscopic diagnosis of PC (MiDPC) on diagnostic\u2212therapeutic management and outcome. Methods: The Veneto region (north-eastern Italy) has been covered by a cancer registry (CR) since 1987. Clinical and oncological data about all cases of PC in the Veneto region from 1987 were extracted from the Veneto CR database. Results: In 2018, 1340 incident cases of PC in the Veneto population were registered (4.1% of all malignant tumors), with an increasing trend in females and stable incidence in males. Five-year OS in patients with PC was 8%. The percentage of MiDPC increased from 44% in 2010 to 60% in 2018 (p = 0.001). MiDPC was higher among patients aged &lt; 75 years old (84.4%) compared to those aged \u226575 years old (38.9%), p = 0.001. Between 2010 and 2018, a significant increase in biopsy on the primary neoplasm (24.9% vs. 13%, p &lt; 0.001) was reported. Patients with MiDPC had higher 5-year survival than patients with no MiDPC (12.9% vs. 1.2%, p &lt; 0.001). Conclusions: The implementation of MiDPC was essential to improve diagnostic\u2212therapeutic pathways and consequently the survival of PC patients.<\/p>\n<p><strong>Pubmed<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36358790\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36358790\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fantin A, Gruppo M, De Simoni O, Lonardi S, Cristofori C, Morbin T, Peserico G, Grillo S, Masier A, Franco M, Pilati P, Guzzinati S, Zorzi M, Rugge M. Cancers (Basel). 2022 Oct 31;14(21):5372. doi: 10.3390\/cancers14215372.<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_helpful_status":1,"footnotes":""},"categories":[398,772,812,860,882],"tags":[],"class_list":["post-3187","post","type-post","status-publish","format-standard","hentry","category-398","category-incidence","category-pancreatic-cancer","category-survival","category-veneto"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Registro Tumori Veneto &#8212; Impact of Microscopic Confirmation on Therapeutic Management of Pancreatic Cancer Patients: Lessons from an Italian Regional Tumor Registry<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.registrotumoriveneto.it\/en\/english\/publications\/research-publications\/2022\/impact-of-microscopic-confirmation-on-therapeutic-management-of-pancreatic-cancer-patients-lessons-from-an-italian-regional-tumor-registry\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Registro Tumori Veneto &#8212; Impact of Microscopic Confirmation on Therapeutic Management of Pancreatic Cancer Patients: Lessons from an Italian Regional Tumor Registry\" \/>\n<meta property=\"og:description\" content=\"Fantin A, Gruppo M, De Simoni O, Lonardi S, Cristofori C, Morbin T, Peserico G, Grillo S, Masier A, Franco M, Pilati P, Guzzinati S, Zorzi M, Rugge M. 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