{"id":3033,"date":"2019-01-23T00:00:50","date_gmt":"2019-01-23T00:00:50","guid":{"rendered":"https:\/\/www.registrotumoriveneto.it\/2019\/01\/23\/trends-of-colorectal-cancer-incidence-and-mortality-rates-from-2003-to-2014-in-italy\/"},"modified":"2019-01-23T00:00:50","modified_gmt":"2019-01-23T00:00:50","slug":"trends-of-colorectal-cancer-incidence-and-mortality-rates-from-2003-to-2014-in-italy","status":"publish","type":"post","link":"https:\/\/www.registrotumoriveneto.it\/en\/english\/publications\/research-publications\/2019\/trends-of-colorectal-cancer-incidence-and-mortality-rates-from-2003-to-2014-in-italy\/","title":{"rendered":"Trends of colorectal cancer incidence and mortality rates from 2003 to 2014 in Italy"},"content":{"rendered":"

Zorzi M, Dal Maso L, Francisci S, Buzzoni C, Rugge M, Guzzinati S; AIRTUM Working Group.<\/em><\/p>\n

Tumori. 2019 Mar 27:300891619838336. doi: 10.1177\/0300891619838336<\/p>\n

<\/p>\n

\u00a0<\/p>\n

Abstract<\/strong><\/p>\n

OBJECTIVE
To evaluate the trends of colorectal cancer (CRC) incidence and mortality rates from 2003 to 2014 in Italy by age groups and regions.<\/p>\n

METHODS\u00a0
We used the data of 48 cancer registries from 17 Italian regions to estimate standardized incidence and mortality rates overall and by sex, age groups (<50, 50-69, 70+ years), and geographic area (northwest, northeast, center, south, and islands). Time trends were expressed as annual percent change in rates (APC) with 95% confidence intervals (95% CI).<\/p>\n

RESULTS
Incidence rates decreased from 104.3 (2003) to 89.9 \u00d7 100,000 (2014) in men and from 64.3 to 58.4 \u00d7 100,000 in women. Among men, incidence decreased during 2007-2010 (APC -4.0, 95% CI -6.0 to -1.9) and 2010-2014 (APC -0.7, 95% CI -1.4 to 0.0), while in women it linearly decreased during the whole period (APC -1.1, 95% CI -1.4 to -0.8). Mortality rates showed a linear reduction both in men (APC -0.7, 95% CI -1.0 to -0.3) and women (APC -0.9, 95% CI -1.2 to -0.6) and decreased respectively from 41.1 to 39.2 \u00d7 100,000 and from 24.6 to 23.1 \u00d7 100,000. In the 50- to 69-year-old range (screening target age), incidence showed a prescreening increase, followed by a peak after screening started, and a decline thereafter. Incidence and mortality rates significantly decreased in all areas but in the south and islands, where incidence increased and mortality remained stable.<\/p>\n

CONCLUSIONS
A renewed commitment by all regional health systems to invest in primary (i.e., lifestyle) and secondary (i.e., screening programs) prevention is of utmost importance.<\/p>\n

\u00a0<\/p>\n

Pubmed<\/strong>: https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30917756<\/a><\/p>\n

\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"

Zorzi M, Dal Maso L, Francisci S, Buzzoni C, Rugge M, Guzzinati S; AIRTUM Working Group. 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