{"id":2840,"date":"2018-01-24T13:00:40","date_gmt":"2018-01-24T13:00:40","guid":{"rendered":"https:\/\/www.registrotumoriveneto.it\/2018\/01\/24\/characteristics-of-the-colorectal-cancers-diagnosed-in-the-early-2000s-in-italy-figures-from-the-impact-study-on-colorectal-cancer-screening\/"},"modified":"2018-01-24T13:00:40","modified_gmt":"2018-01-24T13:00:40","slug":"characteristics-of-the-colorectal-cancers-diagnosed-in-the-early-2000s-in-italy-figures-from-the-impact-study-on-colorectal-cancer-screening","status":"publish","type":"post","link":"https:\/\/www.registrotumoriveneto.it\/en\/incidenza\/characteristics-of-the-colorectal-cancers-diagnosed-in-the-early-2000s-in-italy-figures-from-the-impact-study-on-colorectal-cancer-screening\/","title":{"rendered":"Characteristics of the colorectal cancers diagnosed in the early 2000s in Italy. Figures from the IMPACT study on colorectal cancer screening"},"content":{"rendered":"<p><em>Zorzi M, Mangone L, Anghinoni E, Baracco S, Borciani E, Caldarella A, Falcini F, Fanetti AC, Ferretti S, Giorgi Rossi P, Michiara M, Randi G, Stracci F, Vicentini M, Zucchetto A, Zappa M and IMPATTO COLONRETTO working group.<\/em><\/p>\n<p><em>Epidemiol Prev 2015; 39(3) Suppl 1:108-14<\/em><\/p>\n<p><!--more--><\/p>\n<p>\u00a0<\/p>\n<p><strong>Abstract<\/strong><\/p>\n<p>The impact of organized screening programmes on colorectal cancer (CRC) can be observed at a population level only several years after the implementation of screening. We compared CRC characteristics by diagnostic modality (screen-detected, non-screen-detected) as an early outcome to monitor screening programme effectiveness.\u00a0Data on CRCs diagnosed in Italy from 2000 to 2008 were collected by several cancer registries. Linkage\u00a0with screening datasets made it possible to divide the cases by geographic area, implementation\u00a0of screening, and modality of diagnosis (screen-detected, non-screen-detected). We compared the main\u00a0characteristics of the different subgroups of CRCs through multivariate logistic regression models.<br \/>The study included 23,668 CRCs diagnosed in subjects aged 50-69 years, of which 11.9% were screendetected\u00a0(N=2,806), all from the North-Centre of Italy. Among screen-detected CRCs, we observed a\u00a0higher proportion of males, of cases in the distal colon, and a higher mean age of the patients. Compared\u00a0with pre-screening cases, screen-detected CRCs showed a better distribution by stage at diagnosis\u00a0(OR for stage III or IV: 0.40, 95%CI: 0.36-0.44) and grading (OR for poorly Differentiated CRCs\u00a0was 0.86, 95%CI: 0.75-1.00).<br \/>Screen-detected CRCs have more favourable prognostic characteristics than non-screen-detected cases.\u00a0A renewed effort to implement screening programmes throughout the entire country is recommended.<\/p>\n<p>\u00a0<\/p>\n<p><strong>e&amp;p:<\/strong>\u00a0<a href=\"http:\/\/bit.ly\/2BfcVbA\">http:\/\/bit.ly\/2BfcVbA<\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<pre>\u00a0<\/pre>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zorzi M, Mangone L, Anghinoni E, Baracco S, Borciani E, Caldarella A, Falcini F, Fanetti AC, Ferretti S, Giorgi Rossi P, Michiara M, Randi G, Stracci F, Vicentini M, Zucchetto A, Zappa M and IMPATTO COLONRETTO working group. Epidemiol Prev 2015; 39(3) Suppl 1:108-14<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_helpful_status":1,"footnotes":""},"categories":[405,723,772,13,780,847],"tags":[],"class_list":["post-2840","post","type-post","status-publish","format-standard","hentry","category-405","category-colorectal-cancer","category-incidence","category-incidenza","category-italy","category-screening"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Registro Tumori Veneto &#8212; Characteristics of the colorectal cancers diagnosed in the early 2000s in Italy. Figures from the IMPACT study on colorectal cancer screening<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.registrotumoriveneto.it\/en\/incidenza\/characteristics-of-the-colorectal-cancers-diagnosed-in-the-early-2000s-in-italy-figures-from-the-impact-study-on-colorectal-cancer-screening\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Registro Tumori Veneto &#8212; Characteristics of the colorectal cancers diagnosed in the early 2000s in Italy. 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