National level
Decree of the President of the Council of Ministers (DPCM) no. 308 dated 10 December, 2002 establishing the “Regulations for the definition of the model and the procedures for keeping the register of asbestos-related mesothelioma cases”. The national registry was formerly maintained by ISPEL - Italian National Institute for Occupational Safety and Prevention (today by INAIL - National Institute for Insurance against Accidents at Work).
The Register collects all cases of malignant mesothelioma of the pleura, peritoneum, pericardium and tunica vaginalis of the testicle. The aim of the register are:
a) to establish mesothelioma incidence in Italy;
b) to acquire information relating to previous asbestos exposure of registered cases;
c) to contribute to the assessment of the effects of industrial use of asbestos and to the identification of sources of pollution;
d) to promote research projects for the assessment of the association of mesothelioma cases and asbestos exposure.
Legislative decree (D. Lgs.) no. 81/2008 confirmed the National Register of Malignant Mesotheliomas – ReNAM (art. 244) at INAIL; INAIL collaborates with the Regional Operating Centres (CORs) in the national surveillance system of the incidence of mesothelioma.

Regional level
The Mesothelioma Register of the Veneto Region was established by the Regional Council of Veneto (DGRV) n. 538/2001; the registry is placed within the Epidemiological Department - Azienda Zero in Padova.